Studies were conducted to evaluate absorption, translocation, and metabolism of ¹⁴C-CGA 362622 when foliar applied to cotton, peanut, jimsonweed, and sicklepod. Differential metabolism is the basis for tolerance in cotton and jimsonweed. In addition, cotton absorbs less herbicide compared with the other three species, thus aiding in tolerance. Only jimsonweed translocated appreciable herbicide (25%) out of treated leaves and acropetally to the meristematic tissue where the herbicide was quickly metabolized. No plant species translocated over 2% of applied radioactivity below the treated leaves. Most of the metabolites formed by the four species were more polar than CGA 362622 and averaged 51, 48, 30, and 25% of the radioactivity detected in the treated leaves of cotton, jimsonweed, peanut, and sicklepod, respectively. The half-life of CGA 362622 was estimated to be 0.8, 1.9, 4, and 6 d in treated leaves of cotton, jimsonweed, sicklepod, and peanut, respectively.

Nomenclature: CGA 362622, N-[(4,6-dimethoxy-2-pyrimidinyl)carbamoyl]-3-(2,2,2-trifluoroethoxy)-pyridin-2-sulfonamide sodium salt; jimsonweed, Datura stramonium L. DATST; sicklepod, Senna obtusifolia (L.) Irwin and Barnaby CASOB; cotton, Gossypium hirsutum L. ‘Stoneville 474’; peanut, Arachis hypogaea L. ‘NC 10C’.